Artemisia scoparia – A new source of artemisinin
نویسندگان
چکیده
منابع مشابه
Artemisia annua (Sweet Annie), Other Artemisia Species, Artemisinin, Artemisinin Derivatives, and Malaria
This paper reviews the use of whole-plant Artemisia annua (sweet Annie) as it pertains to malaria including history, chemistry, clinical efficacy, pharmacokinetics, dosing, safety, and resistance. Artemisinin, the sesquiterpene lactone found in the plant, and various semi-synthetic variants of it used as critical drugs around the world for malaria are discussed in comparison to the whole plant....
متن کاملExamining The Extraction Of Artemisinin From Artemisia Annua Using Ultrasound
Artemisinin suppresses the life-cycle of the plasmodium parasite which causes malaria. It is found naturally occurring within the trichome glands of the Artemisia annua plant. Traditional methods for extracting artemisinin are time-consuming and have high environmental impact due to the temperatures and organic solvents which must be employed. Ultrasound decreases these through acoustic streami...
متن کاملPhytotoxicity of major constituents of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit.
The phytotoxicity of the three major monoterpene constituents of the essential oil from leaves of Artemisia scoparia Waldst. & Kit. (redstem wormwood) was investigated. GC/GC-MS analysis revealed that the essential oil (yield 0.84%) is a complex mixture containing 19 monoterpenes, 7 sesquiterpenes and 15 other compounds--aliphatic alcohols, ketones, aromatic hydrocarbons and esters. The three m...
متن کاملProficiencies of Artemisia scoparia against CCl4 induced DNA damages and renal toxicity in rat.
BACKGROUND Artemisia scoparia is traditionally used in the local system of medicine in kidney disorders. This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol extract against carbon tetrachloride (CCl4) provoked DNA damages and oxidative stress in kidneys of rat. METHODS Dried aerial parts of A. scoparia were powdered and extracted with methanol to obtain t...
متن کاملHepatoprotective effects of artemisia scoparia against carbon tetrachloride: an environmental contaminant.
The hepatoprotective activity of crude extract of artemisia scoparia (aerial parts) was investigated against experimentally produced hepatic damage using carbon tetrachloride (CCl4) as a model hepatotoxin. CCl4 at the dose of 1.5 ml/kg, produced liver damage in rats as manifested by the rise in serum levels of AST and ALT to 395 +/- 110 and 258 +/- 61 IU/l (mean +/- SEM; n = 10) respectively, c...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2010
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v5i1.4901